Cannabinoids are the chemical compounds found in cannabis plants that interact with the body’s endocannabinoid system, influencing everything from mood to pain relief. With the rise of cannabis products on the market, understanding the differences in potency and effects of cannabinoids can help consumers make informed choices. Here, we’ll rank six popular cannabinoids—CBD, CBN, Delta 8, Delta 9, THCa, and THCP—from least psychoactive to most, while exploring their unique benefits and effects.
1. CBD (Cannabidiol): The Non-Psychoactive All-Star
Psychoactivity: None
Effects: Relaxation, reduced anxiety, and pain relief
Health Benefits: Known for its therapeutic properties, CBD has been widely studied for its potential to alleviate anxiety, reduce inflammation, improve sleep, and even help manage epilepsy.
CBD is the go-to cannabinoid for those seeking the benefits of cannabis without the “high.” It’s commonly found in oils, tinctures, edibles, and topical products, making it a versatile choice for wellness-focused individuals.
2. CBN (Cannabinol): The Sleep Aid
Psychoactivity: Very mild
Effects: Sedation, relaxation, and improved sleep quality
Health Benefits: CBN is often dubbed the “sleep cannabinoid” due to its potential to support restful sleep. It may also offer mild pain relief and anti-inflammatory benefits.
CBN forms as THC ages and oxidizes, which makes it less psychoactive but still effective for relaxation and sleep. It’s often used in conjunction with CBD in nighttime formulas.
3. THCa (Tetrahydrocannabinolic Acid): The Precursor
Psychoactivity: None (in raw form)
Effects: None when unheated; psychoactive when decarboxylated into THC
Health Benefits: THCa has shown promise for anti-inflammatory, neuroprotective, and anti-nausea properties.
THCa is the acidic form of THC found in raw cannabis. It only becomes psychoactive when exposed to heat, such as through smoking, vaping, or cooking. When smoked, THCa converts to Delta 9 THC, delivering a psychoactive experience very similar to traditional Delta 9 THC. Consuming raw THCa via juices or capsules may provide therapeutic benefits without any “high.”
4. Delta 8 THC: The Mellow High
Psychoactivity: Moderate
Effects: Euphoria, relaxation, and mild mental clarity
Health Benefits: Delta 8 THC is believed to help with pain relief, appetite stimulation, and stress reduction while being less anxiety-inducing than Delta 9 THC.
Delta 8 THC offers a gentler psychoactive experience compared to its more potent counterpart, Delta 9 THC. It’s an excellent choice for those new to cannabis who want a manageable high.
5. Delta 9 THC: The Classic High
Psychoactivity: High
Effects: Euphoria, heightened sensory perception, and relaxation
Health Benefits: Delta 9 THC is known for its ability to relieve pain, reduce nausea, and stimulate appetite. It’s also commonly used recreationally for its strong psychoactive effects.
Delta 9 THC is the most well-known cannabinoid associated with the traditional cannabis “high.” While its effects can be intense, many users also appreciate its therapeutic benefits.
6. THCP (Tetrahydrocannabiphorol): The New Frontier
Psychoactivity: Extremely high (up to 30x more potent than Delta 9 THC)
Effects: Intense euphoria, relaxation, and heightened sensory perception
Health Benefits: Preliminary research suggests THCP may have significant pain-relieving and anti-inflammatory properties, but more studies are needed.
THCP is a newly discovered cannabinoid that binds more effectively to the body’s CB1 receptors, making it far more potent than Delta 9 THC. This cannabinoid is still being explored, but its potential for therapeutic applications is exciting.
Key Takeaways
- CBD and CBN are ideal for those seeking non-psychoactive or mildly psychoactive options for wellness and sleep.
- THCa provides raw benefits without the “high” unless activated by heat. Smoking it converts THCa to Delta 9 THC, offering effects similar to traditional Delta 9 THC.
- Delta 8 THC and Delta 9 THC offer varying levels of psychoactivity, with Delta 8 being milder and Delta 9 providing the classic cannabis experience.
- THCP represents the cutting edge of cannabinoid research with unparalleled potency.
Whether you’re seeking relaxation, pain relief, or a potent psychoactive experience, understanding the ranking and effects of cannabinoids ensures you’ll find the right product for your needs. Always start with a low dose when trying a new cannabinoid, and consult a professional if you’re unsure about what’s best for you.